Skip to product information

SkinCeuticals Retinol 0.5

Serums & Treatments • Cream • 1 oz
Regular price $90
20% OFF with code PREFALL20 View Details
EARN +900 POINTS WHEN PURCHASING THIS PRODUCT
Product Benefits
  • Helps smooth the appearance of fine lines, wrinkles, and other visible signs of aging
  • Promotes cell turnover to refine rough texture and reveal a smoother complexion
  • Targets discoloration and uneven skin tone for a more radiant, even-looking complexion
Expert Review
Helps clear congestion and reduce breakouts by keeping pores clear and encourages natural exfoliation for a fresher, healthier-looking.

Checkout With Your HSA/FSA

Maximize your pre-tax HSA/FSA dollars.

  1. Select "Pay another way" or checkout as a guest.

    The checkout payment step, with a cursor clicking 'Pay another way' below a saved card.
  2. Select the "Flex - Pay with HSA/FSA" option.

    The checkout payment options, with 'Flex | Pay with HSA/FSA' selected below the credit card option.
  3. Enter your HSA/FSA card details.

    The Flex HSA/FSA payment form, with card number, expiration, security code, country and ZIP code fields.

In stock & ships same day! *

Free Shipping for US Orders

Free Returns No questions Asked

Earn rewards with our Loyalty Program

Authenticity Guaranteed
All products at DermStreet are authentic guaranteed. Trusted by thousands, we’ve earned over 1,600+ 5 star reviews.

SkinCeuticals Retinol 0.5 is a high-performance night-time treatment designed for those with some retinol experience, offering a potent concentration of 0.5% pure retinol to refine skin texture, reduce the appearance of fine lines and wrinkles, and improve overall radiance. This advanced formula accelerates cell turnover, unclogs pores, and targets uneven skin tone while being balanced with soothing ingredients to help minimize irritation. Ideal for those looking to enhance their retinol routine, it promotes a smoother, clearer, and more youthful-looking complexion.

Dry Skin
Oily Skin
Normal Skin
Combination Skin
  • 5 stars: 14 (78%)
  • 4 stars: 4 (22%)
  • 3 stars: 0 (0%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
A
Anaya

I moved up to this after using a lower strength retinol, and it’s been a really good next step. My skin feels smoother and I’ve noticed my tone looks more even.

J
Journey

I’ve been using this a few nights a week and my skin texture has improved a lot. It helped with rough patches and my skin looks more refined overall.

J
Jessie

My skin was starting to look a little dull and uneven, and this helped bring it back. I wake up and my skin looks smoother and more refreshed.

N
Natalee

I like that this is strong enough to make a difference but still manageable. My skin feels softer and some of my fine lines look less noticeable.

M
Marina

I’ve had issues with clogged pores and breakouts, and this helped clear things up over time. My skin looks clearer and feels more balanced.

B
Braelyn

I’ve been using this consistently and my skin just looks better overall. It feels smoother, looks brighter, and has improved in texture over time.

L
Lila

I was a little nervous to move up in retinol strength, but this has been working well for me. My skin looks more even and has a healthier glow now.

H
Hayley

This product is amazing it’s effective without being drying. I’ve already noticed a difference in my fine lines!

C
Cheyanne

I love how well this works without causing irritation. It’s the perfect balance not too strong, yet very effective. I use it three times a week.

E
Esther

With consistent use, my skin looks clearer and smoother. Just make sure to apply it on dry skin for the best results.

M
Mikayla

It’s a potent formula, but when paired with Triple Lipid Restore, the results are incredible! For reference, I’m 45 and love how my skin looks.

L
Libby

This retinol is gentle yet powerful. A little goes a long way, so this tube will last forever. Highly recommend!

C
Camryn

After just one night, my skin started flaking, so I eased into it with once a week use. Now, I apply it three times a week with no peeling, and my skin is softer and more even-toned. Stick with it it’s worth it!

K
Karlie

I switched from another brand’s 0.5 retinol to SkinCeuticals’ version three months ago, and I’m so glad I did! Even using it just once or twice a week, my skin looks fresher, younger, and naturally radiant. People have even complimented my glow! At night, I pair it with Resveratrol BE and Triple Lipid Restore for extra nourishment.

A
Adelaide

I started with the 0.3 retinol since my skin is very sensitive, and it worked great. Recently, I upgraded to 0.5, and I can already see my skin looking brighter! I only use it three times a week since it’s quite strong, but I love the results. SkinCeuticals never disappoints!

B
Barbara

This is a go-to product for me I can always count on SkinCeuticals to deliver results.

C
Cynthia

I’m loving this retinol! It brightens my skin without irritation. I use it twice a week, alternating with a chemical exfoliator, and on other nights, I stick to just my night cream. My skin has never looked better!

M
Marianna

I was hesitant to switch to a stronger retinol, but my skin adjusted surprisingly well. I alternate between this retinol and SkinCeuticals glycolic acid, and the morning after using retinol, my skin looks smoother, with fine lines visibly softened. Definitely repurchasing!

Shop by Category
Skin care is a personal journey and we're here to guide you along the way. Live chat our skin care experts for more help.

Get In Touch
How Can We Help?
Have questions, concerns, or need help choosing a product? Our skincare experts are here for you.

Kits & Bundles