SkinCeuticals A.G.E. Interrupter Advanced

Serums & Treatments • Cream • 1.7 oz

$185

20% Off with code LUCKY20

EARN +1850 POINTS WHEN PURCHASING THIS PRODUCT

Product Benefits

Helps smooth fine lines and deep wrinkles caused by collagen breakdown and glycation
Delivers intense moisture to help combat dryness and improve skin comfort
Supports the skin’s structure to improve elasticity and resilience for a more youthful look

Expert Review

Specially designed for those experiencing loss of elasticity, dryness, and visible aging concerns.

Product variants

In stock & ships same day! *

Free Shipping for US Orders

Free Returns No questions Asked

Earn rewards with our Loyalty Program

Authenticity Guaranteed

All products at DermStreet are authentic guaranteed. Trusted by thousands, we’ve earned over 1,600+ 5 star reviews.

SkinCeuticals A.G.E. Interrupter Advanced is a powerful anti-aging cream designed to target visible signs of aging caused by advanced glycation end-products (A.G.E.), a major contributor to skin aging. Formulated with a high concentration of Proxylane™, wild fruit flavonoids, and glycyrrhetinic acid, this rich cream helps improve the appearance of wrinkles, restore skin firmness, and enhance overall radiance. It deeply nourishes and hydrates while strengthening the skin’s barrier, making it ideal for mature skin experiencing loss of elasticity, dryness, and dullness.

All Skin Types

Aqua / Water, Hydroxypropyl Tetrahydropyrantriol, Glycerin, Propylene Glycol, Stearic Acid, Butyrospermum Parkii Butter / Shea Butter, Hydroxyethylpiperazine Ethane Sulfonic Acid, Palmitic Acid, Pentylene Glycol, Oleyl Alcohol, Arachidyl Alcohol, Myristyl Myristate, Panthenol, Niacinamide, Dimethicone, Isononyl Isononanoate, Bis-peg/ppg-16/16 Peg/ppg-16/16 Dimethicone, Glyceryl Stearate, Candelilla Cera / Candelilla Wax, Behenyl Alcohol, Peg-100 Stearate, Sodium Polyacrylate, Pentaerythrityl Tetraisostearate, 4-t-butylcyclohexanol, Arachidyl Glucoside, Caprylyl Glycol, Xanthan Gum, Chlorphenesin, Myristic Acid, Caprylic/capric Triglyceride, Glycyrrhetinic Acid, Parfum / Fragrance, Sorbitol, Vaccinium Myrtillus Fruit Extract, Potassium Hydroxide, Adenosine, Citric Acid, Punica Granatum Fruit Extract, Limonene, Coumarin, Linalool, Pentaerythrityl Tetra-di-t-butyl Hydroxyhydrocinnamate

Apply SkinCeuticals A.G.E. Interrupter Advanced to clean, dry skin by massaging a thin, even layer onto the face, neck, and décolleté twice daily. Use it after applying serums and before sunscreen in the morning or as the final step in your nighttime skincare routine. For best results, incorporate it consistently to help improve skin firmness, hydration, and overall radiance.

All Orders Are Shipped Same Day

Free U.S. Shipping Orders Over$50 View Our Shipping Policy

Return Policy: View Our Return Policy

How Can We Help?

Do you have any questions, concerns, or need assistance choosing a product? We're here to help!

Shop SkinCeuticals

20% Off with code LUCKY20

A groundbreaking skincare innovation formulated to replenish, nourish, and visibly transform aging skin. Infused with a unique ratio of lipids, including 2% pure ceramides, 4% natural cholesterol, and 2% fatty...

3 LEFT

3.9

(10 reviews)

SkinCeuticals Triple Lipid Restore 2:4:2 Anti-Aging Cream

Regular price $155

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals A.G.E. Advanced Eye Complex is a highly effective eye treatment designed to target the visible signs of aging around the delicate eye area. Packed with a powerful blend of...

#1 Trending

4.9

(10 reviews)

SkinCeuticals A.G.E. Advanced Eye

Regular price $116

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals Hyaluronic Acid Intensifier Multi-Glycan is a powerful serum designed to restore hydration, enhance skin firmness, and visibly improve texture. Formulated with a unique blend of ingredients, including multi-glycans and...

New Arrival

4.7

(10 reviews)

SkinCeuticals Hyaluronic Acid Intensifier Multi-Glycan

Regular price $120

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals Emollience Moisturizer is a rich and nourishing face cream designed to hydrate and soften dry, sensitive, or combination skin. Enriched with a blend of natural extracts including sea algae,...

staff pick

4.08

(12 reviews)

SkinCeuticals Emollience Moisturizer

Regular price $78

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals Silymarin CF is a powerful antioxidant serum designed to target oily and blemish-prone skin. Formulated with 0.5% silymarin (milk thistle extract), 15% L-ascorbic acid (vitamin C), 0.5% ferulic acid,...

4.77

(13 reviews)

SkinCeuticals Silymarin CF

Regular price $182

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals A.G.E. Interrupter Advanced is a powerful anti-aging cream designed to target visible signs of aging caused by advanced glycation end-products (A.G.E.), a major contributor to skin aging. Formulated with...

4.82

(11 reviews)

SkinCeuticals A.G.E. Interrupter Advanced

Regular price $185

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals Phloretin CF with Ferulic Acid is a highly potent antioxidant serum formulated to protect the skin against environmental damage and visible signs of aging. This advanced serum combines 2%...

4.69

(13 reviews)

SkinCeuticals Phloretin CF with Ferulic Acid

Regular price $182

Same day shipping*
20% Off with code LUCKY20

SkinCeuticals Phyto A+ Brightening Treatment is a lightweight, oil-free moisturizer designed to improve skin clarity, soothe irritation, and enhance overall radiance. Formulated with a blend of azelaic acid, alpha arbutin,...

4.85

(13 reviews)

SkinCeuticals Phyto A+ Brightening Treatment

Regular price $110

Same day shipping*

Shop SkinCeuticals

After using this cream for about a month, I’m in love. It’s richer than most creams but still easy to apply. It leaves my skin feeling soft and dewy without any greasy residue. Highly recommend!

I’ve been using SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream daily for years, always after applying my SkinCeuticals serum. At 77, my skin is wrinkle-free and radiant truly an incredible product!

This cream is amazing! Within just a week, my skin looked brighter and more hydrated.

I’ve only used SkinCeuticals A.G.E. Interrupter Advanced Corrective Cream a few times, but it’s already my go to for dry, flaky winter skin. My complexion feels smooth, hydrated, and glowing. So glad I found this!

The thick, creamy texture of this moisturizer is perfect for deep hydration, especially on my forehead. It absorbs quickly and works beautifully year round.