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iS Clinical Super Serum Advance +

Serums & Treatments • Serum
Regular price $104
30% OFF with code OCTFEST30 View Details
EARN +1040 POINTS WHEN PURCHASING THIS PRODUCT
Product Benefits
  • Helps to fade the appearance of discoloration, hyperpigmentation, and uneven skin tone, revealing a brighter and more luminous complexion.
  • Deeply hydrates and plumps the skin, improving moisture retention and enhancing overall skin texture and elasticity
  • Minimizes the appearance of fine lines, wrinkles, and other signs of aging while promoting a smoother, more radiant, and rejuvenated complexion
Expert Review
Provides powerful antioxidant protection against environmental stressors, free radicals, and UV damage, helping to prevent premature aging and maintain skin health
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Authenticity Guaranteed
All products at DermStreet are authentic guaranteed. Trusted by thousands, we’ve earned over 1,600+ 5 star reviews.

Experience the transformative power of iS Clinical Super Serum Advance +, a cutting-edge skincare solution designed to address multiple signs of aging. This clinically advanced formula combines potent botanical ingredients and scientifically proven actives to deliver unparalleled results. Featuring a powerful blend of antioxidants, vitamins, and peptides, this serum helps to minimize the appearance of fine lines and wrinkles, improve skin texture and tone, and promote a more youthful complexion. With regular use, you can expect firmer, brighter, and healthier-looking skin. Harness the power of advanced skincare technology with iS Clinical Super Serum Advance + and unlock your skin's true potential.

All Skin Types
Mature Skin
SENSITIVE SKIN
  • 5 stars: 44 (96%)
  • 4 stars: 0 (0%)
  • 3 stars: 2 (4%)
  • 2 stars: 0 (0%)
  • 1 star: 0 (0%)
J
Jennifer Napierskie
My holy grail

I’ve been looking for a vitamin c serum for years that is truly effective. My aesthetician recommended this and I haven’t looked back since! It goes on smoothly, not sticky or smelly.

A
Anonymous
The serum is great!!

The serum is great!! However this time when I ordered from dermstreet the dropper was defective which caused half the serum to leak which was very disheartening!

j
jbug
Meh

After reading all the positive reviews I was hopeful. I am 66 with the usual aging skin issues. This was my least favorite serum I have ever used. It seemed to absorb into my fingers before I could even get it on my face, then absorbed into my face leaving no traces - and no results after 4 months of use.

N
Nessasx0
Acne Prone Skin Approved!

If you have acne prone skin, hormonal and or adult acne and have tried other LAA serums with no hope, you need to try this serum. This is the only LAA that my skin will tolerate without causing acne or deep bumps underneath my jawlines. If anything, I believe this has help manage my acne due to the zinc property along with the other soothing ingredients. This does not burn, it dries to a matte finish. Though, I would prefer a glow finish. It has a slight distinct smell but doesn't bother me. It has significantly brighten my dark spots within days! If I have have future dark spots, I know this serum will take care of it. It has ZERO pore clogging ingredients and I would consider this to be gentle on the skin.

L
Lauren H.
My favorite vitamin c serum

My dermatologist recommend I start using this daily. It has done amazing work healing my skin and giving me a nice glow. This is definitely good for preventing signs of aging .

N
Natalia
Natalia

My skin loves everything from IS CLINICAL! And this serum is no exception. Powerful, absorbs quickly and penetrates deeply. Works quickly, improves skin tone and texture. Will buy again.

L
Liz
Worth the expense

Super pricey but so effective that I am on my third bottle.

L
Leah Odonoghue
Great serum

I have used the proheal serum also, and this serum is more hydrating and seems to absorb better.

B
Becca
I love it so far

I just recently added this to my regime and I love it, not too heavy which is a game changer for me.

C
Christy Geddes
Questionable

I don’t believe the product is full strength it seems watered down compared to same product I purchased in facial spa.

S
Sarah

I absolutely adore this product.

M
Mary
IS Clinical Super Serum Advance Plus

This product effectively tackles a range of skin concerns, including fine lines and acne.

V
Virginia
An essential addition to your skincare regimen

This product is absolutely amazing!

S
Stephanie
The Holy Grail!

I absolutely adore this serum that my dermatologist recommended!

P
Pippa

I stumbled upon this amazing product that I absolutely adore. It has the ability to give my skin a beautiful dewy appearance and prepares it perfectly for the day ahead.

N
Nicola
It does everything!

I have a deep affection for IS Clinical Super Serum Advance. It effectively enhances my skin's radiance without leaving any greasy or shiny residue.

M
Molly
The Top Serum

For years, I have been using IS Clinical Active Serum, Hydra Serum, and a moisturizer on my face and d�colletage as part of my nightly routine. The results have been amazing - I wake up with healthy, glowing skin that has just the right amount of natural moisture. My makeup goes on more smoothly and I often receive compliments on my youthful-looking skin, despite being 50 years old. While I occasionally experiment with other products, I always come back to this regimen because it truly delivers results. My tip for others is to use all three products together and to incorporate the exfoliant at least once a week. Using each product on its own simply doesn't compare to the results of using them all together. It's definitely worth it!

T
Theresa
The iS Clinical Super Serum Advance + is extremely effective.

Since I started using this product, I've noticed an increase in compliments about my skin. I'm considering trying a similar product for my body too.

D
Diana
Clinical love

I absolutely adored using this line in my business. It is incredibly lightweight and simply marvelous, making it worth every single penny.

A
Anna

You won't regret purchasing this product as it is truly valuable! Even my esthetician noticed a remarkable improvement in my skin. However, it is important to use it consistently in order to witness the desired results.

P
Penelope
It works effectively.

Although it is expensive, I cannot imagine going without it after witnessing the amazing results. The PIH fades rapidly and your skin appears more rejuvenated within a few months. I apply it before my moisturizer at night and under my sunscreen during the day. It may be a bit of a splurge, but it is definitely worth it if you are seeking a reparative treatment that is gentle and non-drying.

K
Kylie
Indubitably, a super serum.

I have been a loyal user of this product for many years and I absolutely adore it. Despite trying out six other C serums, this one stands out as the best, which is why I always come back to it. I even watched a YouTube video where they compared different C serums on a piece of fruit, and this one clearly outperformed the rest. Additionally, a little goes a long way with this product, so it lasts a significant amount of time.

R
Rebecca
Top-rated Vitamin C Serum

I adore the way it gives my skin a radiant glow and helps to diminish my dark spots.

V
Vanessa
Amazing serum for mature skin

I am absolutely in love with this product! It effectively hydrates my skin, diminishes fine lines, and enhances my complexion's evenness.

C
Carol
Great

Your skin deserves kindness and it will reward you with visible results that make the price and longevity worth it. I have been using it for years and every night, I top it off with a moisturizing night cream.

V
Victoria
This product is excellent for firming and brightening the skin!

I have been using this product (almost) every night for approximately a year. I genuinely believe it has been beneficial in reducing my discoloration, melasma, and acne scars. My skin appears more radiant. However, I cannot use it on its own due to the extremely dry climate I live in. I need to apply a thicker moisturizer on top of it. I alternate between this product and retinol at night, using each about twice a week. This routine helps revitalize my skin after the retinol has a tendency to dry it out.

C
Caroline
Perfect for those with oily skin!

I have been using this product for several years now. Instead of using it every night, I try to use it a few times a week due to its high cost. However, I have noticed that my skin readily absorbs the beneficial vitamins it provides.

S
Stephanie
I absolutely adore this serum!!!!

This product is adored by my skin, leaving it looking youthful and radiant.

A
Ava
Improves the condition of my skin

I am extremely fond of this product. It has been incredibly effective in clearing my skin and reducing the appearance of red marks caused by acne. After using it, my skin looks radiant and healthy.

R
Rachel
My dermatologist recommended this product and it gives my skin a radiant appearance.

Applying a few drops onto your cleansed skin before bed will result in a rejuvenated appearance the next morning. Your skin will appear more hydrated and fine lines will be less noticeable. Without a doubt, this has become my go-to product. Among all the products I have tested, this one truly delivers! Although it may be pricey, it is definitely worth the investment.

W
Wendy
I intend to purchase this item once more, and I highly recommend it to anyone.

This product is truly amazing. I can't even begin to imagine how my skin would look without it.

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