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iS Clinical Poly-Vitamin Serum

Serums & Treatments • Serum
Regular price $78
30% OFF with code PREFALL30 View Details
EARN +780 POINTS WHEN PURCHASING THIS PRODUCT
Product Benefits
  • Reduces the appearance of fine lines and wrinkles, promoting a smoother and more youthful complexion
  • Retains moisture in the skin, keeping it hydrated and plump
  • Evens out skin tone and improve the appearance of hyperpigmentation and discoloration
Expert Review
Suitable for all skin types, the serum addresses multiple skin concerns, including aging, dehydration, and environmental damage.
Size

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All products at DermStreet are authentic guaranteed. Trusted by thousands, we’ve earned over 1,600+ 5 star reviews.
iS Clinical Poly-Vitamin Serum is a potent blend of vitamins, antioxidants, and botanical extracts designed to nourish and revitalize the skin. This lightweight serum improves skin texture, tone, and elasticity while reducing the appearance of fine lines and wrinkles. With vitamins A,,B3, along with hyaluronic acid and soothing botanicals, it provides comprehensive skincare benefits for a more radiant and youthful complexion. Suitable for all skin types, this serum hydrates, protects, and rejuvenates, promoting healthier-looking skin with every use.
All Skin Types
Mature Skin
SENSITIVE SKIN
  • 5 stars: 9 (50%)
  • 4 stars: 6 (33%)
  • 3 stars: 1 (6%)
  • 2 stars: 1 (6%)
  • 1 star: 1 (6%)
i
ira
ira

I apply it at night and my face immediately burns, but in the morning I have a baby face. The most unexpected effect is a face that is tightened to a shine, fresh and plump, wrinkles are smoothed out. I am delighted and shocked:

I
Ira
Love

I am very pleased with this serum, it suited me perfectly. It exfoliates the skin gently, but is very active, so we don’t pour it on, but apply no more than 3 drops to the face and quickly rub it in.

i
ira
IS CLINICAL

The most unexpected effect is a face that is tightened to a shine, fresh and plump, wrinkles are smoothed out. I am delighted and shocked :)

K
Kennedy

I was using a retinol cream, but it made my face extremely dry and irritated. Now, I'm using a serum with 0.5% retinol, and I've gradually built up to using it every night without experiencing any redness or irritation!

M
Molly
Shine

I absolutely adore this product

A
Allie

Oh, I absolutely adore this product! It deeply hydrates my skin overnight, leaving me with a healthy, plump, and glowing complexion by morning. I'm completely hooked and won't be giving this up anytime soon.

P
Priscilla

Outstanding Product
I'm thoroughly impressed by this little gem. I appreciate that it contains all the beneficial ingredients for your skin. It's quite potent and tingles slightly upon application. I'm excited to try other products from this line.

K
Kamryn

Fantastic
My skin absolutely loves this serum. At 47, I struggle with problematic, hormonal skin that tends to break out from almost everything. After trying countless products, I found this serum to be magical. It keeps my skin clear without causing the major peeling and redness that strong retinol products often do. When I ran out for a few weeks, my menopausal acne flared up on my chin, but within a week of resuming use, my skin calmed down and was back under control. For me, this serum, combined with Youth Complex at night and Active Serum and Hydra Cool Serum during the day, works wonders.

J
June

Absolutely Adore This Product

I've been incorporating this product into my nightly routine for nearly two years. I apply it beneath my primary anti-aging serum for an added boost. At 51, I truly believe it provides an extra layer of vitamins and nourishment to my skin. My dermatologist recommended it, and I couldn't be happier. Over time, I've noticed a significant improvement in my skin, and I can't imagine my routine without it. I use several products from the iS line, and they consistently exceed my expectations!

M
Macie

Dewiness
I'm really enjoying this serum. I've only just begun using it, but I already feel dewy and hydrated. Plus, I love all the benefits it offers!

A
Alyssa

I adore this serum! It keeps my skin calm and clear—absolutely love it!

G
Gracelyn

The Ultimate Serum for Enhancing Autumn Skin Care
I rely on this serum to strengthen my skin as I transition from summer to the cooler, drier months. The results are immediate, and a small amount is very effective. With mature skin, I find that all iS products work wonders for me. Absolutely love it!

S
Selah

Fantastic Product
I've been incorporating this into my morning routine for about a month now. It's non-greasy, which is perfect for my very oily skin. Just one small pump is enough to cover my face and neck. A little truly goes a long way, making it a great value for the price.

K
Kaliyah

Absolutely love it! Just a small amount makes a big difference. It causes a slight redness and mild tingling on my skin, but that fades quickly. By morning, my skin is hydrated and glowing!

H
Hazel

Excellent! Is Clinical is one of my favorite brands. It's extremely effective and lives up to its description. It's worth every penny. This serum is especially great for nighttime use since it contains retinol.

M
Miah

Outstanding Product
On the advice of my aesthetician, I decided to try this product for the first time. Living in a cold climate with dry, sensitive skin, I found it to be incredibly beneficial. I've been applying it only at night, and typically, I would wake up with tightness and numerous dry patches on my cheeks. However, since incorporating this product into my routine, I no longer face that dryness. Additionally, the pores around my nose have become visibly smaller. While some users reported experiencing redness, I only noticed it during my first application, and it subsided within 15-20 minutes, never to return. This is a fantastic product, and I will definitely be ordering it again.

I
Isabella

Absolutely love this product! This is my third time buying it. It leaves my skin looking flawless and glass-like. There's a slight tingling sensation when first applied, but it disappears within seconds.

J
Jaslene

A New Addition to My Morning Skincare Routine

When I turned 50 in October 2021, I decided it was time to upgrade my morning skincare regimen. I had already been using iSClinical Super Serum Advance every morning, so incorporating iSClinical’s hydrating Poly-Vitamin Serum seemed like a natural next step. I apply it over the Super Serum and before my sunscreen. So far, so good! You never know if products will work for you, but the iSClinical line has been a reliable staple for me for the past 8 years.

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