Last reviewed October 28, 2026 · 9-minute read
The short answer: Fall is one of the best times to start retinol. The sun is weaker, and the air isn't yet as dry as it gets in deep winter. Start with the lowest-strength formula you can find, use a pea-sized amount at night two to three times a week, buffer with moisturizer, and build up slowly. Wear broad-spectrum SPF 30+ every morning, and skip retinoids if you're pregnant.
If you've been meaning to start retinol "someday," this is your sign. Dermatologist Shereene Idriss, MD, put it plainly in a recent fall skincare roundup: "fall is the time to start retinol if you have not yet introduced one into your routine." With summer sun behind us and indoor heating not yet at full blast, skin has an easier window to adjust.
Retinol has earned its reputation for softening the look of fine lines, refining texture and evening tone, but it also has a reputation for flaking, stinging and redness when people rush it. We sorted through the retinol lineup at DermStreet with one goal: doing it the easy way, with the right strength, the right schedule and the right support.
Why is fall the best time to start retinol?
✔ Less sun. Retinoids can make skin more sensitive to the sun, according to the American Academy of Dermatology (AAD). Shorter days and less time outdoors make that easier to manage.
✔ Kinder air. Dr. Idriss notes that early in fall the heat isn't fully on and the air is less dry, so skin adjusts more easily than it would mid-winter.
✔ Time to build tolerance. Starting now gives you weeks to work up to regular use before the driest months arrive.
✔ Repair season. Fall and winter are when many people focus on fading summer's leftover sun spots and uneven texture.
What is retinol, and how is it different from other retinoids?
"Retinoids" is the umbrella term for vitamin A-based skincare. The AAD explains that prescription retinoids include tretinoin, tazarotene and trifarotene, while adapalene is available both by prescription and over the counter. Retinol is a gentler, over-the-counter retinoid commonly used for uneven tone, pigmentation and texture. Bakuchiol is a plant-based ingredient often used as a retinol alternative.
| Type | Strength | Best for |
|---|---|---|
| Low-strength retinol (about 0.1%–0.25%) | Gentlest | First-timers and sensitive skin |
| Moderate retinol (about 0.3%–0.5%) | Step up | Skin that tolerates a starter formula |
| Retinal (retinaldehyde) | Often positioned as a step up from retinol | Experienced users ready to build |
| Prescription retinoids | Strongest | Under a dermatologist's care |
One useful tip from the AAD: over-the-counter labels aren't required to state the retinol percentage, so when you're starting out, choose the least intense formula you can find. For a deeper primer, see our guide to the power of retinol.
How do you start retinol without irritation?
✔ Night only. The AAD recommends using retinoids at night.
✔ Go slow. Start two to three times a week for a couple of weeks, then increase only if your skin isn't overly irritated. Dermatologist Paul Yamauchi, MD, recommends exactly this approach in AAD guidance.
✔ Pea-sized amount. More product doesn't mean faster results, just more irritation.
✔ Protect the delicate spots. Dermatologist Marjon Vatanchi, MD, suggests applying petroleum jelly or a hydrating moisturizer under the eyes and at the corners of the nose and mouth before your retinoid.
✔ Moisturize. Starting slowly and following with moisturizer helps limit irritation.
✔ Separate your exfoliants. Use acids or peels on different nights from your retinol.
Some dryness and mild flaking in the first weeks is common. If you notice burning, significant redness or dark marks, stop and talk to a dermatologist. The AAD notes that in deeper skin tones, irritation can trigger hyperpigmentation, so watch closely.
Who should use retinol, and who should skip it?
Good candidates: people with mild fine lines, uneven tone or texture, enlarged-looking pores, or mild breakouts.
Skip it or check with a dermatologist first if:
✔ You're pregnant, trying to conceive or breastfeeding. The AAD states that retinoids should not be used during pregnancy.
✔ You have significant redness or inflammation, possibly rosacea, or very dry, allergy-prone skin.
✔ You have moderate to severe acne scarring or hormonal acne.
✔ You're already using a prescription retinoid or strong exfoliating treatments.
If you want a gentler path, a bakuchiol formula, or a non-retinoid like the azelaic acid in our latest guide, can be a good place to start.
The Best Retinol Serums for Beginners at DermStreet
Deals current as of October 28, 2026. DermStreet discounts vary by brand, take one code per item, and may change.
Best First Retinols
-
Dr. Althea 0.1% Gentle Retinol Serum — A true starter: low-strength retinol with bakuchiol, panthenol and allantoin for a soft introduction. Use one to two drops in the evening.
Deal at DermStreet: 25% off with code SPOOKY25 -
ALASTIN Skincare Renewal Retinol 0.25 Serum — A gentle 0.25% retinol cushioned by niacinamide, oat, bisabolol and ceramide NP, designed for sensitive skin and retinol newcomers.
Deal at DermStreet: 25% off with code SPOOKY25 -
PCA SKIN Retinol Treatment for Sensitive Skin — A low-concentration retinol cream with bisabolol, niacinamide, panthenol and ceramide NP that helps calm the look of redness while smoothing texture.
Deal at DermStreet: 27% off with code SPOOKY27
For Dark Spots and Uneven Tone
-
ZO Skin Health Retinol Skin Brightener 0.25% — Encapsulated retinol with bakuchiol and antioxidants to help brighten the look of discoloration and leftover summer sun spots. Contains essential oils, so sensitive skin should patch test.
Deal at DermStreet: 20% off with code SPOOKY20
Ready to Step Up
-
SkinCeuticals Retinol 0.3 — A 0.3% retinol with soothing boswellia and bisabolol, a smart next step once a starter formula feels easy.
Deal at DermStreet: 20% off with code SPOOKY20 -
Obagi RETINOL + PHA Refining Night Cream — Slow-release retinol and gentle polyhydroxy acids in a hydrating cream with squalane and hyaluronic acid, helping refine texture and the look of pores.
Deal at DermStreet: 30% off with code SPOOKY30 -
Hydrinity RetaXome Daily Retinal Hydrator — Retinal paired with niacinamide, ceramides, peptides and ectoin for experienced users who want potency with barrier support.
Deal at DermStreet: 20% off with code SPOOKY20
For the Eye Area
-
Replenix Age Restore Anti-Wrinkle Retinol Eye Repair — Retinol with peptides, hyaluronic acid, green tea and vitamin K to help soften the look of crow's feet. Start once at night.
Deal at DermStreet: 25% off with code SPOOKY25
Shop All Retinol → | Shop Fine Lines & Wrinkles →
How to add retinol to your routine
Weeks 1–2: retinol two to three nights a week. Weeks 3–4: every other night if skin feels comfortable. After that: nightly, or move up in strength once your current formula feels easy.
Morning: Gentle cleanser → antioxidant serum → moisturizer → broad-spectrum SPF 30 or higher, every day, even when it's cloudy. If your skin is sensitive, the AAD suggests a physical sunscreen with zinc oxide and/or titanium dioxide.
Evening (retinol nights): Cleanse → dry skin completely → petroleum jelly or moisturizer on the corners of nose and mouth → pea-sized retinol → moisturizer.
Evening (off nights): Cleanse → hydrating serum → richer moisturizer. Keep exfoliating acids to these nights, a couple of times a week at most. Our dry skin picks pair well with a new retinol habit.
Frequently Asked Questions
Is fall a good time to start retinol?
Yes. Less sun exposure and milder air make fall an easy season for skin to adjust. Start slowly and keep wearing daily SPF.
What strength of retinol should a beginner use?
The lowest strength you can find, often around 0.1% to 0.25%. Move up only after your skin tolerates nightly use comfortably.
How often should I use retinol at first?
Two to three nights a week for the first couple of weeks, then increase gradually if your skin isn't irritated.
Can I use retinol and vitamin C together?
Yes, at different times. Use vitamin C in the morning and retinol at night, followed by moisturizer.
Can I use retinol while pregnant?
No. The American Academy of Dermatology says retinoids should not be used during pregnancy. Ask your doctor about alternatives.
Where can I buy retinol serums?
You can buy authentic, physician-grade retinol serums at DermStreet.com, where licensed estheticians can help you pick a strength. Current deals: Dr. Althea, ALASTIN Skincare and Replenix are 25% off with code SPOOKY25; PCA Skin is 27% off with code SPOOKY27; ZO Skin Health, SkinCeuticals and Hydrinity are 20% off with code SPOOKY20; and Obagi is 30% off with code SPOOKY30 (one code per item).
The Bottom Line
Fall is the friendliest season to start retinol: pick a low strength, go slow, moisturize generously and never skip morning SPF. Give it a few months, then step up only if your skin asks for more. At DermStreet, current deals include 25% off Dr. Althea, ALASTIN and Replenix with SPOOKY25, 27% off PCA Skin with SPOOKY27, 20% off ZO, SkinCeuticals and Hydrinity with SPOOKY20, and 30% off Obagi with SPOOKY30.
Not sure which retinol strength is right for you? Our licensed estheticians at DermStreet can help — call 888-249-2502 or start a live chat.
Shop The Blog
Sources
American Academy of Dermatology. Retinoid or retinol?
American Academy of Dermatology. National Healthy Skin Month: Dermatologists provide tips
Yahoo Lifestyle. Dermatologists Want You to Switch Your Skincare Routine for Fall
This article is for educational purposes and is not medical advice.