Last reviewed October 28, 2026 · 8-minute read
The short answer: Choose Clinique Dramatically Different Moisturizing Lotion+ if your skin runs dry to dry-combination and you want classic, cushiony comfort that softens rough patches. Choose Moisture Surge 100H if you want a lightweight, oil-free gel-cream that floods skin with water-based hydration, works for most skin types and doubles as a quick hydrating mask. Many people use both, by season.
Few moisturizers have the cult standing of Clinique's. One has been the yellow bottle on bathroom counters for decades; the other is the pink jar people buy in multiples. Both are now new arrivals at DermStreet, and the most common question we get about them is simple: which one is right for me?
The answer depends on your skin type, your climate and what you want a moisturizer to feel like. Here's how the two compare, where the rest of Clinique's routine fits in, and how to build a no-fuss Clinique routine that holds up as the weather turns cold.
What makes Clinique different?
Clinique launched in 1968 after a 1967 Vogue article, "Can Great Skin Be Created?", written by beauty editor Carol Phillips with dermatologist Dr. Norman Orentreich. The brand debuted with a 3-step routine and describes itself as the first 100% fragrance-free, dermatologist-developed, customizable skin care system.
That routine still organizes the line today:
✔ Step 1: Facial soap to cleanse.
✔ Step 2: Clarifying lotion to exfoliate daily.
✔ Step 3: Dramatically Different moisturizer to hydrate.
Clinique also sorts skin into four types: Type 1 (very dry to dry), Type 2 (dry combination), Type 3 (combination oily) and Type 4 (oily). Knowing yours makes every product choice below easier.
What is Dramatically Different Moisturizing Lotion+?
This is the moisturizer step of the 3-Step system, made for very dry to dry-combination skin. Its ingredient list leans on time-tested comfort ingredients: glycerin, mineral oil and petrolatum to lock in water, urea to soften rough texture, and sodium hyaluronate for extra hydration.
✔ Supports the moisture barrier and softens dry, rough patches
✔ Lightweight enough for morning and evening
✔ A natural fit for winter, air-conditioned offices and travel
Good to know: the formula contains color additives (Yellow 5, Yellow 6 and Red 33). If you know you react to dyes, patch test first.
What is Moisture Surge 100H?
Moisture Surge 100H Auto-Replenishing Hydrator is Clinique's oil-free gel-cream, and Clinique says it keeps skin hydrated for up to 100 hours. It pairs hyaluronic acid with aloe, caffeine, green tea and a peptide, and it absorbs quickly with a cool, bouncy feel.
✔ Instant, weightless hydration for all skin types
✔ Sits well under makeup and sunscreen
✔ Can be applied in a thicker layer and left on for about five minutes as a hydrating mask
Dramatically Different vs. Moisture Surge: which should you choose?
| Dramatically Different Lotion+ | Moisture Surge 100H | |
|---|---|---|
| Texture | Silky lotion-cream | Oil-free gel-cream |
| Best skin types | Very dry to dry combination | All, including combination and dehydrated |
| How it hydrates | Seals in moisture with emollients and occlusives | Draws in water with humectants like hyaluronic acid and aloe |
| Standout ingredients | Urea, glycerin, petrolatum, sodium hyaluronate | Hyaluronic acid, aloe, caffeine, green tea |
| Best season | Fall and winter | Year-round; ideal in heat and humidity |
Our take: if your skin feels tight and flaky, especially once the heat comes on, reach for Dramatically Different. If your skin is thirsty but gets shiny with richer creams, Moisture Surge is the better match. On very dry winter days, try Moisture Surge first and Dramatically Different on top of the driest areas. For more cold-weather strategy, see our winter skin barrier guide.
Who should use Clinique, and who should skip it?
Great for: people who want a simple, reliable routine; dry or combination skin that needs steady hydration; and anyone who prefers fragrance-free basics. A simple moisturizer is also an easy partner for the stronger actives in many routines, like retinoids and vitamin C.
Think twice if: you're sensitive to dyes (Dramatically Different contains them) or to methylisothiazolinone, a preservative listed in All About Clean Liquid Facial Soap. If you have very oily, breakout-prone skin, you may prefer the lighter Moisture Surge over the lotion.
The Best Clinique Skincare to Try at DermStreet
Deals current as of October 28, 2026. DermStreet discounts vary by brand, take one code per item, and may change.
Cleanse
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Clinique All About Clean Liquid Facial Soap — Step one of the system, with a soft lather that lifts away oil and buildup while aloe and sodium hyaluronate help skin stay comfortable. Gentle enough for twice-daily use.
Deal at DermStreet: 20% off with code SPOOKY20
Moisturize
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Clinique Dramatically Different Moisturizing Lotion+ — The classic yellow bottle for dry to dry-combination skin, with urea and glycerin to soften and comfort rough patches.
Deal at DermStreet: 20% off with code SPOOKY20 -
Clinique Moisture Surge 100H Auto-Replenishing Hydrator — An oil-free gel-cream with hyaluronic acid and aloe that delivers fast, weightless hydration. Leave a thick layer on for about five minutes as a quick hydrating mask.
Deal at DermStreet: 20% off with code SPOOKY20
Treat and Perfect
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Clinique All About Eyes Eye Cream With Vitamin C — A lightweight eye cream with a vitamin C derivative and caffeine to help brighten and depuff. More in our dark circles guide.
Deal at DermStreet: 20% off with code SPOOKY20 -
Clinique Even Better Makeup Broad Spectrum SPF 15 — A buildable foundation with vitamin C derivatives that helps even the look of tone and dark spots. Wear your SPF 30+ underneath; makeup alone doesn't give full protection.
Deal at DermStreet: 20% off with code SPOOKY20
Shop All Clinique → | Shop Dry Skin →
How to build a Clinique routine
Morning: All About Clean Liquid Facial Soap → serum (vitamin C is a good choice) → All About Eyes → Moisture Surge 100H or Dramatically Different → broad-spectrum SPF 30 or higher → Even Better Makeup if you wear foundation.
Evening: Cleanse → treatment serum or retinoid → All About Eyes → Dramatically Different for dry skin, or Moisture Surge for combination skin.
Seasonal swap: as indoor heating kicks in, move from Moisture Surge alone to Moisture Surge layered under Dramatically Different, or switch to Dramatically Different entirely. For more texture-friendly options, browse our dehydrated skin and moisturizer collections.
Frequently Asked Questions
Is Moisture Surge or Dramatically Different better for dry skin?
Dramatically Different Moisturizing Lotion+ is designed for very dry to dry-combination skin and seals in moisture. Moisture Surge 100H adds lightweight hydration and suits most skin types. Very dry skin often does best with both layered.
Can I use Moisture Surge 100H and Dramatically Different together?
Yes. Apply Moisture Surge first for water-based hydration, then Dramatically Different on top, focusing on dry areas.
Is Clinique fragrance-free?
Clinique describes its original 3-Step system as 100% fragrance-free. Always check individual ingredient lists, especially if you're also sensitive to dyes or preservatives.
What are the Clinique skin types?
Type 1 is very dry to dry, Type 2 is dry combination, Type 3 is combination oily and Type 4 is oily. Use your type to choose product strengths and textures.
Can I use Moisture Surge as a mask?
Yes. Apply a thicker layer and leave it on for about five minutes, then pat in the excess.
Where can I buy Clinique skincare?
You can buy authentic Clinique at DermStreet.com, a physician-grade skincare retailer with licensed estheticians who can help you pick the right products for your skin type. Clinique is currently 20% off with code SPOOKY20 (one code per item).
The Bottom Line
Pick Dramatically Different for dry, rough skin that needs comfort, and Moisture Surge 100H for fast, weightless hydration that works for nearly everyone. Pair either with a gentle cleanser and daily SPF, and you have a routine that holds up all winter. Clinique is currently 20% off at DermStreet with code SPOOKY20.
Not sure which Clinique moisturizer fits your skin type? Our licensed estheticians at DermStreet can help — call 888-249-2502 or start a live chat.
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Sources
Clinique. Cult Classic: 3-Step Skin Care System
Wikipedia. Clinique
This article is for educational purposes and is not medical advice.